Miami CTSI

CTSI Pilot Awardee Receives Five-Year American Cancer Society Grant for Prostate Cancer Research

05.31.2019

Ranjith Ramasamy, M.D., urologic surgeon and assistant professor in the Department of Urology at University of Miami Health, is the recipient of a prestigious new honor from the American Cancer Society (ACS): a five-year grant to facilitate his research on innovative treatment options for Castration-Resistant Prostate Cancer (CRPC).

In 2018, Dr. Ramasamy and his research partner Dr. Himanshu Arora received a Pilot Award from the University of Miami Clinical & Translational Science Institute (CTSI) for their study on the therapeutic role of Nitric Oxide (NO) in regulating the tumor microenvironment of CRPC. The CTSI Pilot Award gave Dr. Ramasamy and Dr. Arora the seed money necessary to help continue their research on advanced prostate cancer treatment options.

The CTSI provided valuable grant writing preparation and feedback for Dr. Ramasamy and Dr. Arora, giving them an opportunity to work closely with CTSI Grant Writing Mentor, Professor Emeritus Mary Lou King, Ph.D. Their cutting-edge research has also received tremendous support from Dipen Parekh, M.D., professor and chair in the Department of Urology, Joshua M. Hare, M.D., and Nobel Laurette and renowned scientist Professor Andrew V. Schally.

The resources available at the University of Miami and CTSI led to a fruitful outcome for Dr. Ramasamy and Dr. Arora to advance their research. Being awarded a prestigious five-year $729,000 Clinical Scientist Grant from the American Cancer Society provides Dr. Ramasamy and Dr. Arora the critical resources to study combination therapies for advanced prostate cancer patients and potentially opens the door for more effective treatment options.

“The ACS grant is going to provide us with a huge push to explore several aspects of NO-based therapy,” says Dr. Ramasamy. “This includes but is not limited to the use of genetically engineered CRPC-specific mouse models, patient-derived xenograft models, completing our pre-clinical students and moving forward with initiating clinical trials.”

Dr. Ramasamy and his research team anticipate that combination therapy could be a more direct treatment approach with better outcomes for CRPC patients. He credits a supportive and innovative University of Miami culture with helping to propel this research forward.

“We’d like to thank Sylvester Comprehensive Cancer Center and University of Miami for providing this amazing work environment,” says Dr. Ramasamy. “It will continue to inspire us to keep exploring and soon come up with new therapy options for patients with CRPC.”

Can CTSI Help Your Research?
Researchers at University of Miami can tap into resources at the CTSI, utilizing a variety of tools and resources. In addition to connecting teams of researchers to help them expand the scope and research of their projects, the CTSI also offers grant and research writing assistance, clinical trial resources and community partner connections.

To learn more about CTSI, please call 305-243-5096 or email CTSIservices@med.miami.edu.

E-mail a Friend